|1.||New year and our 20th Anniversary, Thomas F. Lüscher, pulmonary hypertension|
PMID: 33382058 doi: 10.14744/AnatolJCardiol.2021.1 Page 1
|2.||Classification of heart failure: A farewell to ejection fraction?|
Thomas F. Lüscher
PMID: 33382057 doi: 10.14744/AnatolJCardiol.2020.70138 Pages 2 - 6
|3.||A meta-analysis of randomized controlled trials investigating tirofiban combined with conventional drugs by intracoronary administration for no-reflow prevention|
Qian Zeng, Long-Dan Zhang, Wei Wang
PMID: 33382055 doi: 10.14744/AnatolJCardiol.2020.99469 Pages 7 - 16
|4.||Sex difference in clinical outcomes of Chinese patients with atrial fibrillation and coronary stenting according to age|
Jian-Yong Zheng, Dong-Tao Li, Yu Chen, Yi-Da Tang, Cheng-Jun Guo, Yun-Dai Chen, Zhi-Min Ma, Tian-Chang Li
PMID: 33382053 doi: 10.14744/AnatolJCardiol.2020.80930 Pages 17 - 23
Objective: Sex differences in the clinical outcomes of patients with atrial fibrillation (AF) and coronary stenting should be assessed according to age.
Methods: We analyzed the clinical data of all patients with nonvalvular AF who underwent coronary stenting between January 2010 and June 2015 in 12 hospitals of Beijing, China.
Results: A total of 2,146 patients (71.8% men and 28.2% women) were included in the study. The mean age of the patients was 66.6±9.4 years. Women in this study were older and had higher prevalence of hypertension, diabetes, chronic kidney disease (CKD), and anemia. Smoking history was found to be higher in men, and women were less likely to be current smokers. The mean follow-up duration was 39.7 months. Women younger than 65 years had a remarkably higher mortality (11.2% vs. 5.3%, p=0.012) and a significantly lower rate of repeat revascularization (1.6% vs. 6.3%, p=0.034) than men. Female gender remained an independent predictor for all-cause mortality [hazard ratio (HR)=2.03, 95% confidence interval (CI): 1.093.79, p=0.025], along with heart failure (HR=3.64, 95% CI: 2.026.57, p<0.001) and CKD (HR=2.46, 95% CI: 1.095.57, p=0.031) after multivariate regression analysis. No significant difference was noted between men and women with regard to mortality, ischemic events, and major bleeding in elderly patients.
Conclusion: In Chinese patients younger than 65 years with AF and coronary stenting, female gender was independently associated with increased mortality; men were more likely to receive repeat revascularization possibly due to the current smoking. Whether it was a biological difference or a recognition disparity of the disease between men and women warrants further investigation.
|5.||Chronic thromboembolic pulmonary hypertension in patients with persistent chest symptoms after acute pulmonary embolism|
Elif Sahutoglu, Esin Tuncay, Gülfidan Aras, Esin Yentürk, Dilek Kanmaz, Hurrem Gul Ongen, Zeki Ongen
PMID: 33382052 doi: 10.14744/AnatolJCardiol.2020.69057 Pages 24 - 29
Objective: This study aimed to analyze the role of chronic thromboembolic pulmonary hypertension (CTEPH) in patients with persistent chest symptoms after acute PE.
Methods: Patients aged between 18 and 80 years who were followed up for acute PE were screened for chest symptoms which persisted after the anticoagulation treatment. Patients suffering other types of pulmonary hypertension (PH) or metastatic malignancies were excluded in this study. Demographic and functional data of patients included this study were collected. The patients underwent transthoracic echocardiography and ventilation/perfusion (VQ) scans. Also, invasive hemodynamic studies were done to patients with intermediate/high probability of VQ scans.
Results: Of the 140 patients screen for this study, 29 patients (Female/Male=16/13) with mean age of 56.1±11.2 years and follow-up time of 35.1±17.7 months met the inclusion criteria. The mean systolic pulmonary artery blood pressure (sPAP) on transthoracic echocardiography was 28.9±4.9 mm Hg (range=2040 mm Hg). Furthermore, intermediate or high probability of VQ scans was detected in 2 patients, who were subsequently diagnosed with CTEPH (6.9%) via right heart catheterization.
Conclusion: CTEPH was diagnosed at a low rate in patients with persistent chest symptoms after the anticoagulation treatment for PE. CTEPH is still an elusive entity, which requires a multidisciplinary and invasive approach.
|6.||How did the updated hemodynamic definitions affect the frequency of pulmonary hypertension in patients with systemic sclerosis?|
Alper Sarı, Yusuf Ziya Şener, Berkan Armağan, Levent Kılıç, Ergün Barış Kaya, Vedat Hekimsoy, Ömer Karadağ, Şule Apras Bilgen, Sedat Kiraz, Ihsan Ertenli, Lale Tokgozoğlu, Ali Akdoğan
PMID: 33382047 doi: 10.14744/AnatolJCardiol.2020.46625 Pages 30 - 35
Objective: Pulmonary hypertension (PH) is a one of the major causes of death in patients with systemic sclerosis (SSc). In this study, we investigated the impact of updated hemodynamic definition proposed by the 6th PH World Symposium (6th WSPH) on the frequency of PH and its subtypes in patients with SSc.
Methods: Patients with SSc admitted between 2015 and 2019 and who underwent right heart catheterization (RHC) were included. The frequency of PH and its subgroups based on the hemodynamic definitions of both 2015 European Society of Cardiology/European respiratory Society (ESC/ERS) PH guidelines and 6th WSPH was compared.
Results: Of the 65 patients with SSc, 23 (35.4%) had normal mean pulmonary arterial pressure (mPAP), 20 (30.8%) had mildly elevated mPAP (2124 mm Hg), and 22 (33.8%) had PH [pulmonary arterial hypertension (PAH) (n=16, 24.6%), group 2 PH (n=5, 7.7%), group 3 PH (n=1, 1.5%)] according to the 2015 ESC/ERS PH definition. Based on the updated criteria, 7 (10.8% of total cohort) additional patients were reclassified as having PH [PAH (n=3), group 2 PH (n=3), group 3 PH (n=1)].
Conclusion: The impact of the updated definition on the frequency of PH and PAH in our cohort was greater than previously reported, which may be caused by the difference in screening strategies for PAH.
|7.||Pulmonary hypertension in patients with sarcoidosis: A single-center experience|
Deniz Kaptan Özen, Bülent Mutlu, Derya Kocakaya, Burak Turan, Sena Sert Şekerci, Berrin Ceyhan
PMID: 33382054 doi: 10.14744/AnatolJCardiol.2020.88054 Pages 36 - 41
Objective: Sarcoidosis is a systemic granulomatous disease rarely complicated by pulmonary hypertension (PH). The prevalence of PH in sarcoidosis is unclear and has differences between ethnic groups. This study aimed to investigate the prevalence and predictors of PH in a Turkish cohort.
Methods: The study included 55 patients with biopsy-proven sarcoidosis in a single center. All patients underwent detailed transthoracic echocardiography (TTE) to assess the probability of PH as recommended. Right heart catheterization (RHC) was performed for patients with intermediatehigh risk of PH. Patients with mean pulmonary artery pressure >20 mm Hg by RHC were defined as PH. Demographic and clinical characteristics, laboratory data, spirometry, 6-min walk test, and TTE were compared between low and intermediatehigh risk PH groups.
Results: The probability of PH was low with 47 patients. Eight patients had intermediatehigh probability of PH, and two of them refused to undergo RHC. Of six intermediatehigh probability patients, three had PH, and all of them had post-precapillary PH. The prevalence of PH in sarcoidosis was 5.5% (3/55). Six-minute walk distance (6 MWD) and diastolic parameters (E/A ratio, E wave, and left atrial volume) were significantly lower, and New York Heart association class and N-terminal probrain natriuretic peptide (NT-proBNP) level were higher in intermediatehigh risk PH patients compared with low-risk PH patients.
Conclusion: The frequency of PH in sarcoidosis was 5.5% in a Turkish cohort. NT-proBNP, 6 MWD, diastolic function parameters, and myocardial strain parameters can be useful predictors of PH in patients with sarcoidosis, besides known echocardiographic parameters.
|8.||Evaluation of radial artery endothelial functions in transradial coronary angiography according to different radial access sites|
Elton Soydan, Mehmet Kış, Mustafa Akın
PMID: 33382049 doi: 10.14744/AnatolJCardiol.2020.59085 Pages 42 - 48
Objective: Radial endothelial dysfunction may occur after transradial coronary angiography (CAG). This study aimed to make a comparative evaluation of the radial endothelial functions before and after catheterization between three different radial access sites: left radial (LR) artery, left distal radial (LDR) artery, and right radial (RR) artery.
Methods: Seventy patients scheduled for elective transradial CAG and intervention from September 6, 2017 to March 6, 2018 were consecutively enrolled. Radial artery endothelial functions of the catheterization arm were measured by flow-mediated vasodilation (FMD) upon admission, at 24 hours, and 2 months following the procedure.
Results: LR access was used in 17 patients, whereas the LDR and the RR access were used in 27 and 26 patients, respectively. Basal radial diameters and FMD median values measured on the intervention arm were found to be similar between groups (LR 3.04±0.29 mm, 13.33%; LDR 2.79±0.31 mm; 13.64%; RR 2.74±0.29 mm; 12.52%, p=0.952). The radial vasodilation percentage change expressed as median decreased in all groups 24 hours after the procedure; however, the one with the LDR access was found to be significantly higher than with the LR (9.7% vs. 6.25% p=0.013) and the RR access (9.7% vs. 3.39 p<0.001). A partial recovery of endothelial functions was seen at 2 months after the procedure, approximating to basal values (11.11%; 12%; 10.62%, p=0.079, respectively).
Conclusion: Radial artery functions deteriorate early after transradial catheterization. The LDR access seems safer than the other conventional radial access sites in terms of preservation of radial endothelial functions.
|9.||An intriguing case of acute coronary syndrome caused by rotten tuna|
Chiara Gargiulo, Silvana De Martino, Alberto Somaschini, Stefano Cornara, Gabriele Crimi
PMID: 33382044 doi: 10.14744/AnatolJCardiol.2020.28934 Pages 49 - 50
|10.||Failed transcatheter mitral valve-in-ring implantation followed by transapical valve-in-valve within the ring and ad hoc paravalvular leak closure|
Beytullah Çakal, Sinem Çakal, Hacı Murat Güneş, Mehmet Onur Omaygenç, Aydın Yıldırım
PMID: 33382050 doi: 10.14744/AnatolJCardiol.2020.59163 Pages 50 - 53
|11.||A rare cause of mitral regurgitation after aortic valve replacement: Iatrogenic mitral valve perforation|
Begüm Uygur, Ömer Çelik, Anıl Şahin, Ali Rıza Demir, Mehmet Ertürk
PMID: 33432932 doi: 10.14744/AnatolJCardiol.2020.31766 Pages 53 - 54
|12.||What is your diagnosis?|
Yavuzer Koza, Ferhat Kanbay, Muhammed Hakan Tas, Fatih Alper
PMID: 33382046 doi: 10.14744/AnatolJCardiol.2020.46151 Page 55
|LETTER TO THE EDITOR|
|13.||Percutaneous left atrial cardiac biopsy under multidectector computed tomography guidance|
Umberto Geremia Rossi, Anna Maria Ierardi, Maurizio Cariati
PMID: 33382048 doi: 10.14744/AnatolJCardiol.2020.53840 Pages 56 - 57
|14.||Shock wave therapy in cardiology: A comment|
Sergei V Jargin
PMID: 33382056 doi: 10.14744/AnatolJCardiol.2020.95071 Pages 57 - 58
|DIAGNOSTIC PUZZLE - ANSWER|
|15.||A 32-year-old woman with worsening dyspnea|
Yavuzer Koza, Ferhat Kanbay, Muhammed Hakan Taş, Fatih Alper
PMID: 33382059 Page 59
|E-PAGE ORIGINAL IMAGES|
|16.||An extremely rare coronary artery anomaly: Monster left anterior descending coronary artery|
Savaş Çelebi, Özlem Özcan Çelebi
PMID: 33382051 doi: 10.14744/AnatolJCardiol.2020.68782 Pages E1 - E2
|17.||Weird pacing spikes|
Chao-Yu Chen, Ju-Yi Chen
PMID: 33382045 doi: 10.14744/AnatolJCardiol.2020.32527 Pages E2 - E3