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Aortic propagation velocity does not correlate with classical aortic stiffness parameters in healthy individuals [Anatol J Cardiol]
Anatol J Cardiol. 2017; 18(5): 340-346 | DOI: 10.14744/AnatolJCardiol.2017.7306  

Aortic propagation velocity does not correlate with classical aortic stiffness parameters in healthy individuals

Hatem Arı1, Fatih Kahraman1, Yasin Türker1, Serdar Güler1, Hasan Aydın Baş2, Doğan Erdoğan1
1Department of Cardiology, Faculty of Medicine, Süleyman Demirel University, Isparta-Turkey
2Department of Cardiology, Isparta State Hospital, Isparta-Turkey

Objective: Aortic stiffness is an important cardiovascular risk marker, which can be determined using different noninvasive techniques. Aortic propagation velocity (APV) has recently been established as a novel echocardiographic parameter of aortic stiffness. This study aimed to investigate the association between APV and the classical echocardiography-derived aortic stiffness parameters, aortic distensibility (AD) and aortic strain (AS), in a group of otherwise healthy individuals.
Methods: In total, 97 consecutive healthy subjects were recruited in this observational study. APV was measured using color M-mode echocardiography from the suprasternal window in the descending aorta. AS and AD were calculated using clinical blood pressure and the M-mode echocardiography-derived aortic diameters. Correlation analyses were performed between cardiovascular risk factors related to increased aortic stiffness (age, obesity, and blood pressure) and measured stiffness parameters (APV, AS, and AD). Correlation analyses were also performed among the measured stiffness parameters.
Results: Good correlation of age, blood pressure, and BMI with AS and AD was observed. One-on-one correlation of age, blood pressure, and BMI with APV was not observed. No correlation was observed between APV and AS (r=–0.05, p=0.6) or between APV and AD (r=–0.17, p=0.8).
Conclusion: Although APV has been proposed as a novel and practical echocardiographic parameter of aortic stiffness, especially in patients with coronary artery disease, correlations between classical stiffness parameters (AS and AD) and APV were absent in healthy individuals at low–intermediate risk. The clinical and research applicability of APV should be further evaluated.

Keywords: aortic stiffness, echocardiography, aortic propagation velocity


Hatem Arı, Fatih Kahraman, Yasin Türker, Serdar Güler, Hasan Aydın Baş, Doğan Erdoğan. Aortic propagation velocity does not correlate with classical aortic stiffness parameters in healthy individuals. Anatol J Cardiol. 2017; 18(5): 340-346

Corresponding Author: Hatem Arı, Türkiye


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