ISSN 2149-2263 | E-ISSN 2149-2271 Home      
 
Volume : 18 Issue : 2 Year: 2017
Current Issue Archive Popular Article Ahead of Print

   
Quick Search





 
Diurnal blood pressure parameters in normal tension glaucoma, primary open angle glaucoma, and healthy subjects [Anatol J Cardiol]
Anatol J Cardiol. 2017; 18(1): 62-67 | DOI: 10.14744/AnatolJCardiol.2017.7562  

Diurnal blood pressure parameters in normal tension glaucoma, primary open angle glaucoma, and healthy subjects

Tolga Kocatürk1, Çağdaş Akgüllü2, Gökhan E. Evliçoğlu3, İmran K. Ömürlü4, Harun Çakmak1, Ufuk Eryılmaz2, Volkan Dayanır5
1Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University; Aydın-Turkey
2Department of Cardiology, Faculty of Medicine, Adnan Menderes University; Aydın-Turkey
3Department of Ophthalmology, Taşköprü State Hospital; Kastamonu-Turkey
4Department of Biostatistics, Faculty of Medicine, Adnan Menderes University; Aydın-Turkey
5Department of Ophthalmology, Batıgöz Hospital; İzmir-Turkey

Objective: The pathophysiology of glaucoma is still undisclosed. Cardiovascular hemodynamic changes are hypothesized to contribute to glaucoma. This study aimed to determine the differences in the diurnal blood pressure (BP) of patients with normal tension glaucoma (NTG), primary open angle glaucoma (POAG), and controls without glaucoma.
Methods: A total of 129 patients were included in this study. The day–night average systolic and diastolic BPs, the day–night average pulse pressures (PPs), the day–night average heart rates, and the percentage of BP decline at night were obtained from the Holter devices and compared. Study design: Prospective, randomized, case-control study.
Results: This study included 43 NTG patients (Group 1), 44 POAG patients (Group 2), and 42 healthy subjects without glaucoma (Group 3). The age (p=0.138) and sex (p=0.216) distributions between the groups were similar. The average day–night PP values of Group 1 were 49.17±9.90 and 46.07±10.84 mm Hg, respectively, while their total average PP was 48.48±9.60, their total average systolic BP was 120.02±12.65, and their night average systolic BP was 111.93±15.87 mm Hg. In Group 2, the average day and night PP values were 54.83±10.35 and 51.73±9.10 mm Hg, respectively, their total average PP was 54.00±9.87, their total average systolic BP was 126.75±11.50, and their night average systolic BP was 119.21±12.38 mm Hg. These differences were statistically significant and the corresponding p values were 0.040, 0.040, 0.037, 0.033, and 0.038.
Conclusion: NTG patients have low diurnal BP parameters, which may reduce their optic nerve perfusion and may be responsible for their glaucomatous visual field damage. (Anatol J Cardiol 2017; 17: 000-00)

Keywords: normal tension glaucoma, primary open angle glaucoma, optic nerve perfusion, blood pressure


Tolga Kocatürk, Çağdaş Akgüllü, Gökhan E. Evliçoğlu, İmran K. Ömürlü, Harun Çakmak, Ufuk Eryılmaz, Volkan Dayanır. Diurnal blood pressure parameters in normal tension glaucoma, primary open angle glaucoma, and healthy subjects. Anatol J Cardiol. 2017; 18(1): 62-67

Corresponding Author: Tolga Kocatürk, Türkiye


TOOLS
Full Text PDF
Print
Download citation
RIS
EndNote
BibTex
Medlars
Procite
Reference Manager
Share with email
Share
Send email to author

Similar articles
PubMed
Google Scholar




 
 
KARE Publishing | Copyright © 2016 Turkish Society of Cardiology